ncRNA name | hsa-miR-137 |
ncRNA Category | miRNA |
Disease name | retinoblastoma (RB) |
Species | Homo sapiens |
Tissues/Cell_line | RB samples, normal retina tissues; RB cell lines WERI-RB1, Y79, SO-RB50 and HXO-RB44; RPE cell line ARPE-19 |
Methods | qRT-PCR, transfection, CCK-8 assay, colony formation assay, transwell assay, Western blot, luciferase reporter assay |
Expression pattern | down-regulated |
Functional description | miR-137 suppresses the proliferation and invasion of RB cells by targeting COX-2/PGE2. |
PubMed ID | 29945115 |
Year | 2018 |
Title | The down-regulation of microRNA-137 contributes to the up-regulation of retinoblastoma cell proliferation and invasion by regulating COX-2/PGE2 signaling. |
Drug-related ncRNA | NO |
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